Phenotyping of the TDP-43 ΔNLS mouse model of ALS

Herman B. Fernandes, Jose Beltran, Mei Kwan, John Shea, Daniel Havas, Afshin Ghavami, Taleen Hanania Amyotrophic lateral sclerosis (ALS) is a neurodegenerative motor neuron disease characterized by specific cell death of the upper and/or lower motor neurons. The...

Phenotyping of a TDP-43 Mouse Model of ALS

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of upper and lower motor neurons producing muscle denervation, motor impairments, and brain atrophy. Deposition of insoluble cytosolic inclusions of Transactive...