Publications

Stay up to date on PsychoGenics’ latest research, press releases, and industry developments in preclinical drug discovery. Combine our expertise with yours to spark the translational power of your next CNS breakthrough.

PUBLICATION

Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer’s Disease Phenotype in APP/PS1 Transgenic Mice

April 29, 2025
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PUBLICATION

Developmental deletion of amyloid precursor protein precludes transcriptional and proteomic responses to brain injury

April 29, 2025
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PUBLICATION

Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer’s Disease Phenotype in APP/PS1 Transgenic Mice

April 29, 2025
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PUBLICATION

Developmental deletion of amyloid precursor protein precludes transcriptional and proteomic responses to brain injury

April 29, 2025
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PUBLICATION

Swedish Alzheimer’s disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways

April 29, 2025
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PUBLICATION

Amyloid precursor protein induces reactive astrogliosis

April 29, 2025
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PUBLICATION

A systematic assessment of robustness in CNS safety pharmacology

October 10, 2024
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PUBLICATION

Immunotherapy Targeting the C-Terminal Domain of TDP-43 Decreases Neuropathology and Confers Neuroprotection in Mouse Models of ALS/FTD

February 20, 2023
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PUBLICATION

The GBA1 D409V Mutation Exacerbates Synuclein Pathology to Differing Extents in two Alpha-Synuclein Models

August 24, 2022
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PUBLICATION

Elevation of brain magnesium with Swiss chard and buckwheat extracts in an animal model of reduced magnesium dietary intake

November 4, 2021
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PUBLICATION

Use of Phenotypic Screening in Mice in the Development of a Novel Non-D2-Receptor-Targeting Drug for the Treatment of Schizophrenia

December 9, 2020
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