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Evaluation of Locomotor and Sensory Recovery in a Cervical Hemi-Contusion Model Using Standardized Methods.

by Desiree Cobb-Olori | Jun 20, 2025

Johana Bastidas1, Megan R. Detloff2, Linda Jones3, Marco Baptista3, Daniel Havas1, Smriti Mongia1, Karim Fouad4, Wolfram Tetzlaff 5, Taleen Hanania11PsychoGenics, Paramus, New Jersey, US, 2Department of Neurobiology & Anatomy, Marion Murray Spinal Cord Research...

Therapeutic Potential of Investigational Drugs for Rett Syndrome Assessed with Behavioral Profiles in Animal Models

by Desiree Cobb-Olori | Jun 9, 2025

Mark Varney1; Alberto Ambesi-Impiombato1; Daniele Mazowiecki1; Taleen Hanania1; Frank Yucca2; Friso Postma2; Daniela Brunner11PsychoGenics, Inc, Paramus, NJ; 2BioXCell, Lebanon, NH, USA. We used data from the SmartCube® platform and in silico AI predictions to...

Behavioral, Electrophysiological, and Biomarker level changes in the rTG4510 Mouse Model of Alzheimer’s Disease #1259

by Desiree Cobb-Olori | Apr 1, 2025

Taleen Hanania, Herman Fernandes, Mei Kwan, Jose Beltran, John Shea, Afshin Ghavami Aims: rTg4510 mice conditionally express mutant human Tau in variousforebrain regions using Tet-off expression system. This model recapitulatestau pathology observed in AD with...

Twenty Years of Huntington’s Disease Research at PsychoGenics

by Desiree Cobb-Olori | Mar 28, 2025

C. Torturo and S. Ramboz Over the course of the past 20 years, CHDI and PsychoGenics have worked closely together on characterizing mouse models of Huntington’s disease. Primarily, the 120 CAG R6/2 model, the B6.Cg-Tg(HDexon1)61Gpb/J mouse line, or R6/1 model, and the...

Behavioral, electrophysiological, and biomarker level changes in the rTg4510 mouse model of Alzheimer’s disease

by Desiree Cobb-Olori | Mar 27, 2025

Taleen Hanania, Herman Fernandes, Mei Kwan, Jose Beltran, John Shea, Afshin Ghavami Objectives: rTg4510 mice conditionally express mutant human Tau in various forebrain regions using Tet-off expression system. This model recapitulates tau pathology observed in AD with...
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